The Graves-Basedow deasese needs very careful preparation before surgery. The monitoring of involution of thyroid gland in this case could be helpful in assesing the appropriate time of peforming surgery. It seems to be useful to do the ultrasound-power-doppler examination in order to see the thyroid tissue blood perfusion that could give the idea of its involution. We give Metizol and Lugol liquid as the preparation. I would appreciate yours experience in evoluation the thyroid involution in such cases.